Sleep Apnoea & Testosterone: The Silent Health Crisis in Men Over 35
- Dr Rui Graça
- Jul 15
- 3 min read
Updated: Jul 16
By MHI Editorial Team | Medical review: Dr Rui Graça, MD, Urologist & Founder | 15 July 2025
Real case insight:
Mr. X, 49, struggled nightly with poor sleep, fatigue, and declining mood.
He never guessed sleep apnoea and low testosterone were secretly undermining his health.
Discover how a timely diagnosis by Dr. Rui led to a dramatic turnaround.

Sleep Apnoea & Testosterone: The Silent Health Crisis in Men Over 35
Scene 1: The Exhaustion No One Connected
Mr. X sighed deeply, confessing...
“Doc, I’m exhausted. I wake multiple times at night, gasping for breath. It's affecting my energy, my job, even my relationships."
Dr. Rui listened intently, responding, "Sleep disturbances like this could be more than just tiredness. Let’s explore the root cause."
Sleep apnoea affects 1 in 5 men over 40, and many don’t realize it can dramatically lower testosterone levels. The resulting fatigue, low libido, and poor mental clarity are often wrongly attributed to aging.
Scene 2: Clues from Conversation & Clinical Tests
“How's your concentration during the day, and any change in libido?” Dr. Rui asked.
“My focus is poor, libido is lower, and honestly, I'm becoming irritable easily,” Mr. X explained.
Dr. Rui ordered comprehensive tests: overnight sleep study, testosterone, cortisol, inflammatory markers, and metabolic function panels.
Mini-explainers: - Sleep study (polysomnography): Identifies sleep apnoea severity by measuring breathing disruptions. - Testosterone & cortisol tests: Poor sleep elevates cortisol and reduces testosterone, significantly affecting overall health.
Your Next Step: From Guessing to Clarity
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Start by answering 12 simple questions to uncover your most likely imbalance:
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Scene 3: Sleep, Hormones & the Missed Diagnosis
One week later, Dr. Rui shared concerning results:
“You have moderate sleep apnoea, causing chronic sleep disruption and significantly reduced testosterone levels. Your cortisol and inflammation markers are also elevated, worsening the cycle."
“Is sleep apnoea causing all this?” asked Mr. X, surprised.
“Exactly. Treating sleep apnoea often helps restore testosterone naturally," Dr. Rui explained.
"We’ll address this comprehensively - initially using CPAP therapy to improve your sleep quality, alongside targeted lifestyle changes to support hormone restoration."
Sleep apnoea disrupts breathing, leading to fragmented sleep, chronic stress response (elevated cortisol), inflammation, and reduced testosterone production. Addressing sleep apnoea can dramatically improve hormonal balance, mood, and overall health.
Scene 4: Follow-Up & Unexpected Bump
Six weeks in, Mr. X noticed some improvements but faced frustration.
“Sleep is better, but I’m still feeling tired at times. Is something off?”
Dr. Rui reassured him, “It's part of the recovery. Let's fine-tune your lifestyle further with specific nutritional support and stress-reducing strategies to enhance your hormonal rebound."
Resolution: 12 Weeks to Better Health
At 12 weeks, Mr. X reported major improvements.
“I’m sleeping deeply, energy and focus are back, and my libido has improved noticeably. It feels like a complete reset."
"Your sleep apnoea is managed, your testosterone is up, and your health is dramatically improved," confirmed Dr. Rui, smiling.
Quick Takeaways: - Sleep apnoea significantly impacts testosterone levels and overall health in men. - Proper diagnosis and treatment of sleep disorders can naturally improve hormonal balance. - Lifestyle and nutritional changes complement medical treatments, greatly enhancing health outcomes.
Disclaimer: This article is for educational purposes only and does not constitute medical advice. Consult a licensed physician for personalised care. Clinical details are composite and privacy-protected. Story reviewed by Dr Rui Graça, MD.
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